Publications

OptiStem began work in March 2009. We will post details of publications arising from our research on this page.

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Title Citation Authors Publication Date
PW1 gene/paternally expressed gene 3 (PW1/Peg3) identifies multiple adult stem and progenitor cell populations Proc Natl Acad Sci U S A. 2011 Jun 27. [Epub ahead of print] Besson V, Smeriglio P, Wegener A,... 27/06/2011
Human embryonic stem-cell derived keratinocytes: how close to clinics? Cell Stem Cell, Volume 6, Issue 1, 8-9 Pellegrini G and De Luca M 08/01/2011
An evolutionarily acquired genotoxic response discriminates MyoD from Myf5, and differentially regulates hypaxial and epaxial myogenesis EMBO Reports, 7 January 2011 [Epub ahead of print] Innocenzi A, Latella L, Messina G,... 07/01/2011
Transcriptome analyses based on genetic screens for Pax3 myogenic targets in the mouse embryo BMC Genomics. 2010 Dec 8;11:696. Lagha M, Sato T, Regnault B, Cumano A,... 28/12/2010
News from the brain: the GPR124orphan receptors directs brain-specific angiogenesis Sci Transl Med. 2(58):58ps53 Dejana E, Nyqvist D 17/11/2010
Megarole for microRNA in muscle disease Cell Metab. ;12(5):425-6. Crist, CG, Buckingham, M 03/11/2010
Direct effects of the pathogenic mutation on satellite cell function in muscular dystrophy Exp Cell Res 316, 3100-3108 (2010) Morgan, JE and Zammit, PS 01/11/2010
The role of wnt signaling in physiological and pathological angiogenesis Circ Res. 107(8):943-52 Dejana E 15/10/2010
Mesenchymal stromal cells: Facilitators of successful transplantation? Cell Stem Cell 7(4):431-42 English K, French A, Wood KJ 08/10/2010
The prolyl isomerase pin1 is involved in terminal differentiation and myocyte enhancer factor 2C function in skeletal muscle cells J. Biol. Chem. Nov 5; 285(45):34518-27 [Epub 2010 Aug 27] Magli A, Angelelli C, Ganassi M,... 27/08/2010
Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells Nature, 466, 978–982 (19 August 2010) Bonfanti P, Claudinot S, Amici AW,... 19/08/2010
Use of magnetically oriented orthogonal collagen scaffolds for hemi-corneal reconstruction and regeneration Biomaterials, 2010 Nov;31(32):8313-22 [Epub 2010 Aug 13] Builles N, Janin-Manificat H,... 13/08/2010
Stem cell therapies to treat muscular dystrophy: progress to date BioDrugs, 24(4):237-47 Meregalli M, Farini A, Parolini D,... 01/08/2010
Evaluation of molecular markers in corneal regeneration by means of autologous cultures of limbal cells and keratoplasty Cornea. 2010 Jul;29(7):715-22. Colabelli Gisoldi RA, Pocobelli A,... 01/07/2010
Limbal Stem-Cell Therapy and Long-Term Corneal Regeneration N Engl J Med, 2010, 363:147-55 Rama P, Matuska S, Paganoni G, Spinelli... 23/06/2010
The Wnt/b-catenin Pathway Modulates Vascular Remodeling and Specification by Upregulating Dll4/Notch Signaling Dev Cell. 18(6):938-49 Corada M, Nyqvist D, Orsenigo F,... 15/06/2010
Characteristics of the early immune response following transplantation of mouse ES cell derived insulin-producing cell clusters PLoS One, 5(6): e10965 Boyd AS, Wood KJ 04/06/2010
Regulation and dysregulation of fibrosis in skeletal muscle Exp Cell Res. 2010 Nov 1;316(18):3050-8. [Epub 2010 Jun 4] Serrano AL, Munoz P 04/06/2010
Combining Stem Cells and Exon Skipping Strategy to Treat Muscular Dystrophy Chapter 15, Muscle gene therapy (Ed. Dongsheny Duan), Springer Meregalli M, Farini A, Torrente Y 01/06/2010
Nitric oxide inhibition of Drp1-mediated mitochondrial fission is critical for myogenic differentiation Cell Death Differ. 2010 Nov;17(11):1684-96. [Epub 2010 May 14] De Palma C, Falcone S, Pisoni S,... 14/05/2010
Co-administration of ibuprofen and nitric oxide is an effective experimental therapy for muscular dystrophy, with immediate applicability to humans Br. J. Pharmacol. 160: 1550-1560, 2010 C. Sciorati, R. Buono, E. Azzoni, S.... 22/04/2010
A Pax3/Dmrt2/Myf5 regulatory cascade functions at the onset of myogenesis PLoS Genetics, 6(4):e1000897 Sato T, Rocancourt D, Marques L,... 01/04/2010
CCM1 regulates vascular-lumen organization by inducing endothelial polarity J Cell Sci. 123(Pt 7):1073-80 Lampugnani MG, Orsenigo F, Rudini N,... 01/04/2010
Nfix Regulates Fetal-Specific Transcription in Developing Skeletal Muscle Cell, Volume 140, Issue 4, 554-566 Messina G, Biressi S, Monteverde S,... 19/02/2010
Atopic dermatitis-like disease and associated lethal myeloproliferative disorder arise from loss of Notch signaling in the murine skin PLoS ONE 5(2): e9258 Dumortier A, Durham A, Di Piazza M,... 18/02/2010
Inactivation of junctional adhesion molecule-A enhance antitumoral immune response by promoting dendritic cell and T lymphocyte infiltration Cancer Res. 2010 Mar 1;70(5):1759-65 [Epub 2010 Feb 16] Murakami M, Francavilla C, Torselli I,... 16/02/2010
Identification and characterization of a non-satellite cell muscle resident progenitor during postnatal development Nat Cell Biol. 2010, 12(3):257-266 [Epub 2010 Jan 31] Mitchell KJ, Pannerec A, Cadot B,... 31/01/2010
Identification and characterisation of a non-satellite cell resident muscle progenitor during postnatal development Nature Cell Biology 12, 257 - 266 (2010) Mitchell KJ, Pannérec A, Cadot B,... 31/01/2010
Repairing skeletal muscle: regenerative potential of skeletal muscle stem cells J. Clin. Invest. 120(1): 11-19 Tedesco FS, Dellavalle A, Diaz-Manera J... 04/01/2010
Pax3:Foxc2 Reciprocal Repression in the Somite Modulates Muscular versus Vascular Cell Fate Choice in Multipotent Progenitors Dev. Cell, 17, 892-899 Lagha M, Brunelli S, Messina G, Kume T... 15/12/2009
An adult tissue-specific stem cell in its niche: a gene profiling analysis of in vivo quiescent and activated muscle satellite cells Stem Cell Res. Oct 28. [Epub ahead of print]. Pallafacchina G, François S, Regnault B... 28/10/2009
Muscle stem cell behaviour is modified by microRNA-27 regulation of Pax3 expression Proc. Natl. Acad. Sci. USA, 106, 13383-13387 Crist CG, Rocancourt D, Montarras D and... 28/07/2009
Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis Development 136, 2815-2823 Driskell RR, Giangreco A, Jensen KB,... 15/07/2009
Mesenchymal stem cells prevent the rejection of fully allogenic islet grafts by the immunosuppressive activity of matrix metalloproteinase-2 and -9 Diabetes, 58(8):1797-806 Ding Y, Xu D, Feng G, Bushell A,... 09/06/2009
Stable vascular connections and remodeling require full expression of VE-cadherin in zebrafish embryos PLoS One., 3;4(6):e5772 Montero-Balaguer M, Swirsding K,... 03/06/2009
Challenges in translational research EMBO Mol. Med. 1, 79-80 Cossu G 08/05/2009
Nerve growth factor promotes in vitro human conjunctival epithelial cells differentiation and mucin gene expression Invest. Ophthalmol. Vis. Sci. 50:4622-4630 Lambiase A, Micera A, Pellegrini G,... 30/04/2009
Gene therapy of inherited skin adhesion disorders: a critical overview Br. J. Dermatol. 161(1):19-24 De Luca M, Pellegrini G and Mavilio F 20/04/2009
The origin of embryonic and fetal myoblasts: a role of Pax3 and Pax7 Genes & Dev. 23, 902-905 Messina G and Cossu G 15/04/2009
The Control of Vascular Integrity by Endothelial Cell Junctions: Molecular Basis and Pathological Implications Dev Cell.,16(2):209-221 Dejana E, Tournier-Lasserve E,... 17/02/2009
Skeletal muscle differentiation of embryonic mesoangioblasts requires Pax3 activity Stem Cells, 27, 157-164 Messina G, Sirabella D, Monteverde S,... 05/01/2009
Organization and signaling of endothelial cell-to-cell junctions in various regions of the blood and lymphatic vascular trees Cell Tissue Res., 335(1):17-25 Dejana E, Orsenigo F, Molendini C,... 01/01/2009
JAM-A promotes neutrophil chemotaxis by controlling integrin internalization and recycling J Cell Sci., 122(Pt 2):268-77 Cera MR, Fabbri M, Molendini C, Corada... 31/12/2008
Isolation and production of cells suitable for human therapy: challenges ahead Cell Stem Cell 4(1):20-26 Ahrlund-Richter L, De Luca M, Marshak... 04/12/2008
Epithelial stem cells in corneal regeneration and epidermal gene therapy J. Pathol. 217:217-228 Pellegrini G, Rama P, Mavilio F and De... 11/09/2008